| Molecular basis of human body odour formation: insights deduced from corynebacterial genome sequences. | |
| | |
MedLine Citation:
|
PMID: 21790661 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
During the past few decades, there has been an increased interest in the essential role of commensal skin bacteria in human body odour formation. It is now generally accepted that skin bacteria cause body odour by biotransformation of sweat components secreted in the human axillae. Especially, aerobic corynebacteria have been shown to contribute strongly to axillary malodour, whereas other human skin residents seem to have little influence. Analysis of odoriferous sweat components has shown that the major odour-causing substances in human sweat include steroid derivatives, short volatile branched-chain fatty acids and sulphanylalkanols. In this mini-review, we describe the molecular basis of the four most extensively studied routes of human body odour formation, while focusing on the underlying enzymatic processes. Considering the previously reported role of β-oxidation in odour formation, we analysed the genetic repertoire of eight Corynebacterium species concerning fatty acid metabolism. We particularly focused on the metabolic abilities of the lipophilic axillary isolate Corynebacterium jeikeium K411. |
| | |
Authors:
|
H Barzantny; I Brune; A Tauch |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-7-25 |
Journal Detail:
|
Title: International journal of cosmetic science Volume: - ISSN: 1468-2494 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
|
Created Date: 2011-7-27 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8007161 Medline TA: Int J Cosmet Sci Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2011 The Authors. ICS © 2011 Society of Cosmetic Scientists and the Société Française de Cosmétologie. |
Affiliation:
|
Institut für Genomforschung und Systembiologie, Centrum für Biotechnologie, Universität Bielefeld, Universitätsstraße 27, D-33615 Bielefeld, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: External validation of pharmacokinetic and pharmacodynamic models of microemulsion and long-chain tr...
Next Document: In vitro human skin permeation and cutaneous metabolism of catechins from green tea extract and gree...