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Molecular allergology in practice: an unusual case of LTP allergy.
MedLine Citation:
PMID:  22360137     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The authors describe an unusual case of LTP allergy. A 35 years old patient presented repeated episodes of angiooedema after food intake and complained 10 years ago of contact urticaria and rhinoconjunctivitis when exposed to cannabis leaves and to marijuana smoke. The suspected responsible foods, such as wheat flour in bread, are known to contain LTR Oral syndrome occurred after ingestion of walnuts. Cutaneous tests confirmed immediate responses to several flours and nuts and also to cannabis leaf and flower. A few months later he had similar accidents following peach ingestion and drinking of beer and several wines which all induced positive skin tests. Serological investigations using ImmunoCAP and ISAC microarray confirmed IgE positivity for n Pru p3, r Cor a 8 and n Art v3. It was assumed that sensitization to LTP, the major allergen of cannabis, was responsible of the primary sensitization and induced further LTP food allergies.
Authors:
C Metz-Favre; G Pauli; J C Bessot; F De Blay
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European annals of allergy and clinical immunology     Volume:  43     ISSN:  1764-1489     ISO Abbreviation:  Eur Ann Allergy Clin Immunol     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-02-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101466614     Medline TA:  Eur Ann Allergy Clin Immunol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  193-5     Citation Subset:  IM    
Affiliation:
Division of Asthma and Allergy, Department of Chest Diseases, University Hospital, Strasbourg, France. Carine.Favre-Metz@chru-strasbourg.fr
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