Document Detail


Molecular adsorbent recirculating system in dealing with maternal Amanita poisoning during the second pregnancy trimester: a case report.
MedLine Citation:
PMID:  14969861     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: A 27-year-old woman in her 20th week of pregnancy was hospitalized because of food poisoning caused by Amanita phalloides. METHODS: Previously extracorporeal purification treatments with 2 times of hemodialysis plus hemoperfusion and a high volume therapeutic plasma exchange (PE) in addition to intensive medication during the first 8 days failed to improve hepatic encephalopathy (HE) and liver function but developed deep coma with severe blood chemistry and signs of threatened abortion. RESULTS: Treatments with intermittent molecular adsorbent recirculating system (MARS) for 3 times resulted in an immediate improvement of liver function and clinical symptoms including HE and threatened abortion until her fully recovery. When the life-threatening maternal illness was cured gestation went on until premature birth at the 36th week of pregnancy, and the infant underwent an undisturbed development. CONCLUSION: MARS method appears to be an optimal therapy for patients with acute liver failure secondary to cytoxic mushroom poisoning during pregnancy.
Authors:
Bang-Fu Wu; Min-Min Wang
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Hepatobiliary & pancreatic diseases international : HBPD INT     Volume:  3     ISSN:  1499-3872     ISO Abbreviation:  HBPD INT     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-02-18     Completed Date:  2004-06-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101151457     Medline TA:  Hepatobiliary Pancreat Dis Int     Country:  China    
Other Details:
Languages:  eng     Pagination:  152-4     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Guangzhou 12th Municipal People's Hospital, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amanita*
Combined Modality Therapy
Female
Follow-Up Studies
Hemoperfusion / methods
Humans
Mushroom Poisoning / diagnosis*,  therapy*
Plasma Exchange / methods
Pregnancy
Pregnancy Complications / diagnosis*,  therapy
Pregnancy Outcome*
Pregnancy Trimester, Second
Renal Dialysis / methods
Risk Assessment
Severity of Illness Index
Sorption Detoxification / methods*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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