| Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic Acid. | |
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MedLine Citation:
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PMID: 19911999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The AIDS Malignancy Consortium undertook a pilot trial of valproic acid among patients with AIDS-associated Kaposi sarcoma (KS). Treatment was associated with low toxicity, but the KS clinical response and KS herpesvirus lytic induction rates were not sufficiently high to meet predefined criteria for efficacy. |
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Authors:
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Maryjo Lechowicz; Dirk P Dittmer; Jeannette Y Lee; Susan E Krown; William Wachsman; David Aboulafia; Bruce J Dezube; Lee Ratner; Jonathan Said; Richard F Ambinder |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 49 ISSN: 1537-6591 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-11-25 Completed Date: 2010-01-27 Revised Date: 2011-03-07 |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: 1946-9 Citation Subset: IM |
Affiliation:
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Winship Cancer Institute, Emory University, Atlanta, Georgia, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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complications* Adult Female Herpesvirus 8, Human / isolation & purification Humans Male Middle Aged Prospective Studies RNA, Viral / analysis Sarcoma, Kaposi / drug therapy* Valproic Acid / therapeutic use* |
| Grant Support | |
ID/Acronym/Agency:
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CA109232/CA/NCI NIH HHS; DE018304/DE/NIDCR NIH HHS; P01 CA081400-04/CA/NCI NIH HHS; P01CA113239/CA/NCI NIH HHS; R01 DE018304-01/DE/NIDCR NIH HHS; R01 DE018304-02/DE/NIDCR NIH HHS; R01 DE018304-03/DE/NIDCR NIH HHS; R01 DE018304-04/DE/NIDCR NIH HHS; R01 DE018304-05/DE/NIDCR NIH HHS; U01 CA070019-08/CA/NCI NIH HHS; U01 CA070019-09/CA/NCI NIH HHS; U01 CA121947-016805/CA/NCI NIH HHS; U01CA070019/CA/NCI NIH HHS; U01CA070047/CA/NCI NIH HHS; U01CA070062/CA/NCI NIH HHS; U01CA071375/CA/NCI NIH HHS; U01CA083035/CA/NCI NIH HHS; U01CA083118/CA/NCI NIH HHS; U01CA121947/CA/NCI NIH HHS; U01CA70054/CA/NCI NIH HHS; UO1CA66535/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/RNA, Viral; 99-66-1/Valproic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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