Document Detail


Molecular Characterization of Bacterial Colonization in the Preterm and Term Infant's Intestine.
MedLine Citation:
PMID:  22576294     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To further define patterns of colonising intestinal microflora in newborn infants utilising molecular methods. METHODS: Ten term and 5 preterm (<32 wk) infants born at the Royal Hospital for Women, Sydney, Australia were enrolled in the present study and followed for 6 mo post partum. Serial stools were collected, DNA was extracted and subjected to PCR-Denaturing Gradient Gel Electrophoresis using a range of primers and sequencing. The effect of gestational length, feeding and delivery method was compared to the pattern of bacterial acquisition. RESULTS: Intestinal bacterial diversity was lower in preterm compared with term infants. For term infants, bacterial DNA detection rates were not associated with feeding or delivery method, although Enterobacteria and Clostridia were commonly identified. The detection rate of Bifidobacteria was lower in preterm infants than term infants. Potential pathogens were detected in preterm infant samples. CONCLUSIONS: Preterm infants frequently have aberrant bacterial colonization of the intestine. Further research is now required to determine if this may contribute to adverse health outcomes.
Authors:
J C Hallab; S T Leach; L Zhang; H M Mitchell; J Oei; K Lui; A S Day
Related Documents :
8817214 - Familial hiatus hernia and gastro-oesophageal reflux.
12142794 - Pneumocystis carinii pneumonia in patients with diamond-blackfan anemia receiving high-...
22377314 - In vivo digestion of infant formula in piglets: protein digestion kinetics and release ...
1032894 - High-pouch imperforate anus treated by electromagnetic bougienage and subsequent perine...
8823924 - Determination of selenium in infant formula and enteral formula by dry ash graphite fur...
12521794 - Clinico-pathological study of causes of perinatal mortality in a developing country.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-11
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  -     ISSN:  0973-7693     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
School of Biochemistry and Biotechnology, University of New South Wales, Sydney, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Combined radio-colour contrast in the examination of ballistic head models.
Next Document:  Amitraz Poisoning.