Document Detail


Molecular and cellular effects of Auger emitters: 2008-2011.
MedLine Citation:
PMID:  22694308     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To review recent Auger emitter research with an emphasis on a review of findings on targeting and accumulation of Auger emitters in tumor cells.
CONCLUSION: Significant progress can be reported for targeting methods and improvements in methods to accumulate Auger emitters in the target cells, as well as advances in dose calculations. These studies further our understanding of how Auger emitters induce cell death at a cellular and molecular level, supporting the targeted radiomedical applications of Auger emitters.
Authors:
Linda S Yasui
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Publication Detail:
Type:  Journal Article; Review     Date:  2012-07-16
Journal Detail:
Title:  International journal of radiation biology     Volume:  88     ISSN:  1362-3095     ISO Abbreviation:  Int. J. Radiat. Biol.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-03     Completed Date:  2013-01-31     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8809243     Medline TA:  Int J Radiat Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  864-70     Citation Subset:  IM; S    
Affiliation:
Department of Biological Sciences, Northern Illinois University, DeKalb, Illinois 60115, USA. lyasui@niu.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Chemistry
Humans
Molecular Targeted Therapy
Nanotechnology
Neoplasms / drug therapy,  pathology*
Physical Processes*

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