Document Detail

Mojave toxin-type ascending flaccid paralysis after an envenomation by a Southern Pacific Rattlesnake in a dog.
MedLine Citation:
PMID:  22316204     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe the clinical presentation and case management of a dog that developed ascending flaccid paralysis after being envenomated by a Southern Pacific rattlesnake.
CASE SUMMARY: A dog was presented after it was bitten by a Southern Pacific rattlesnake. Only mild local edema and a minor coagulapathy developed, which is atypical for the Southern Pacific envenomation where hemotoxic effects are more commonly observed. Instead, a severe, rapidly progressing, ascending flaccid paralysis leading to acute respiratory failure, consistent with Mojave toxin, was seen. The patient was treated with repeated doses of antivenin and supported with mechanical ventilation. Despite clinical improvement of the paralysis over subsequent 3 days and successful weaning off the ventilator, the dog decompensated and succumbed to acute respiratory distress syndrome.
NEW OR UNIQUE INFORMATION PROVIDED: The geographic region where this envenomation occurred has a documented population of Southern Pacific rattlesnakes with Mojave toxin in their venom. To the knowledge of the authors, this is the first reported case in the veterinary literature of an ascending flaccid paralysis, consistent with Mojave toxin, developing after an envenomation by a Southern Pacific rattlesnake.
Sarah R Hoggan; Amy Carr; Karen A Sausman
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2011-08-24
Journal Detail:
Title:  Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)     Volume:  21     ISSN:  1476-4431     ISO Abbreviation:  J Vet Emerg Crit Care (San Antonio)     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2012-02-09     Completed Date:  2012-06-20     Revised Date:  2012-09-10    
Medline Journal Info:
Nlm Unique ID:  101152804     Medline TA:  J Vet Emerg Crit Care (San Antonio)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  558-64     Citation Subset:  IM    
Copyright Information:
© Veterinary Emergency and Critical Care Society 2011.
Emergency Department of California Veterinary Specialists, Murrieta, CA 92562, USA.
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MeSH Terms
Antivenins / therapeutic use
Crotalid Venoms / adverse effects*
Dog Diseases / etiology*,  therapy
Dogs / injuries
Fatal Outcome
Paraplegia / etiology,  therapy,  veterinary*
Respiration, Artificial / veterinary
Respiratory Distress Syndrome, Adult / complications,  veterinary
Snake Bites / complications,  drug therapy,  veterinary*
Reg. No./Substance:
0/Antivenins; 0/Crotalid Venoms; 0/Mojave toxin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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