| Moisturizers, vehicle effects, and photocarcinogenesis. | |
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MedLine Citation:
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PMID: 19148213 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Topically applied formulations (e.g., emollients and moisturizers) may influence the optical physics of skin and therefore the effectiveness of UVR exposures. In this issue, Lu et al. provide evidence for another type of influence by moisturizers, one that does not require the presence of the chemical agent before or during UVR exposure. Several such test agents applied after the completion of a course of UVR enhanced the tumor response in mice, both qualitatively and quantitatively. The study design is rational but the group sizes are modest, the resulting database is therefore limited, and the repeatability is not yet determined. Perhaps most important for the this Journal's readership, the clinical relevance is unknown and deserves detailed examination. |
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Authors:
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Paul Donald Forbes |
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Publication Detail:
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Type: Comment; Journal Article; Review |
Journal Detail:
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Title: The Journal of investigative dermatology Volume: 129 ISSN: 1523-1747 ISO Abbreviation: J. Invest. Dermatol. Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-01-16 Completed Date: 2009-02-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0426720 Medline TA: J Invest Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 261-2 Citation Subset: IM |
Affiliation:
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Charles River Laboratories, Inc., The Center for Photobiology, 905 Sheehy Drive, Horsham, Pennsylvania 19044, USA. don.forbes@crl.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Dermatologic Agents / adverse effects* Emollients / adverse effects* Humans Skin Neoplasms / etiology* Ultraviolet Rays / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Dermatologic Agents; 0/Emollients |
| Comments/Corrections | |
Comment On:
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J Invest Dermatol. 2009 Feb;129(2):468-75
[PMID:
18704106
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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