Document Detail


Moebius syndrome and holoprosencephaly following exposure to misoprostol.
MedLine Citation:
PMID:  20933185     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Moebius syndrome is a rare disease characterized by congenital facial paralysis and abducens palsy. Involvement of other cranial nerves, orofacial dysmorphism, and limb abnormalities are frequently associated. Reported here is the case of a 10-month-old child born with Moebius syndrome and presenting with holoprosencephaly, following exposure in utero to misoprostol. To our knowledge, this is the first published case report describing this association. The etiologic hypotheses of Moebius syndrome are also discussed.
Authors:
Rodrigo Pirmez; Maria Eliza T Freitas; Emerson L Gasparetto; Alexandra P Q C Araújo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  43     ISSN:  1873-5150     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  371-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Affiliation:
Medical School, Federal University of Rio de Janeiro, Rua Paulo Barreto 91, Rio de Janeiro, RJ, Brazil. rodrigopirmez@gmail.com
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