Document Detail


Modulatory effect of coffee fruit extract on plasma levels of brain-derived neurotrophic factor in healthy subjects.
MedLine Citation:
PMID:  23312069     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The present single-dose study was performed to assess the effect of whole coffee fruit concentrate powder (WCFC), green coffee caffeine powder (N677), grape seed extract powder (N31) and green coffee bean extract powder (N625) on blood levels of brain-derived neurotrophic factor (BDNF). Randomly assorted groups of fasted subjects consumed a single, 100 mg dose of each material. Plasma samples were collected at time zero (T 0) and at 30 min intervals afterwards, up to 120 min. A total of two control groups were included: subjects treated with silica dioxide (as placebo) or with no treatment. The collected data revealed that treatments with N31 and N677 increased levels of plasma BDNF by about 31 % under these experimental conditions, whereas treatment with WCFC increased it by 143 % (n 10), compared with baseline. These results indicate that WCFC could be used for modulation of BDNF-dependent health conditions. However, larger clinical studies are needed to support this possibility.
Authors:
Tania Reyes-Izquierdo; Boris Nemzer; Cynthia Shu; Lan Huynh; Ruby Argumedo; Robert Keller; Zb Pietrzkowski
Related Documents :
24011229 - Airborne allergens, endotoxins, and particulate matter in elementary schools, results f...
23583909 - How to improve the reliability of hsa-thiol group determination?
24593239 - Management of guillain-barré syndrome with plasmapheresis or immunoglobulin: our exper...
23244539 - Inulin-enriched pasta improves intestinal permeability and modifies the circulating lev...
23654079 - Soluble cd26 and cd30 levels in patients with common variable immunodeficiency.
23279319 - Serum rantes level influences the response to pegylated interferon and ribavirin therap...
9344709 - Anastomosis between ovarian and mesenteric veins in sheep: induction of a physiological...
14725569 - Relationship between cytokine concentrations (fgf, sicam-1 and scf) in serum, follicula...
6726109 - Inhibitory action of chemically deglycosylated human chorionic gonadotrophin on hormone...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-14
Journal Detail:
Title:  The British journal of nutrition     Volume:  -     ISSN:  1475-2662     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-6     Citation Subset:  -    
Affiliation:
Applied BioClinical, Inc., 16259 Laguna Canyon Road, Irvine, CA 92618, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Activation of the gluteus maximus and hamstring muscles during prone hip extension with knee flexion...
Next Document:  The suitability of the current recommendations for introducing gluten to the diet.