Document Detail

Modulation of nonglobin mRNA levels in erythropoiesis.
MedLine Citation:
PMID:  6500177     Owner:  NLM     Status:  MEDLINE    
During erythropoiesis, the decrease of complexity of a RNA population is an important process as is globin mRNA accumulation. To determine the sequential control process of gene expression, many genomic clones which express in mouse reticulocytes were obtained and used for the titration of each mRNA level in the different stages of erythroid cells. The level of mRNAs of rt-clones decreases depending on the maturation of erythroid cells, and the coordinated and sequential control of this level is likely to be one of the factors affecting this process.
Y Mishina; S Natori; M Obinata
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Developmental biology     Volume:  106     ISSN:  0012-1606     ISO Abbreviation:  Dev. Biol.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-01-23     Completed Date:  1985-01-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372762     Medline TA:  Dev Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  343-50     Citation Subset:  IM    
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MeSH Terms
Cloning, Molecular
Erythroblasts / analysis
Globins / genetics
Leukemia, Experimental / metabolism
Mice, Inbred BALB C
Nucleic Acid Hybridization
RNA, Messenger / analysis,  genetics,  metabolism*
Reticulocytes / analysis
Tissue Distribution
Reg. No./Substance:
0/RNA, Messenger; 9004-22-2/Globins

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