Document Detail


Modulation of event-related desynchronization during motor imagery with transcranial direct current stimulation (tDCS) in patients with chronic hemiparetic stroke.
MedLine Citation:
PMID:  22791228     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Electroencephalogram-based brain-computer interface (BCI) has been developed as a new neurorehabilitative tool for patients with severe hemiparesis. However, its application has been limited because of difficulty detecting stable brain signals from the affected hemisphere. It has been reported that transcranial direct current stimulation (tDCS) can modulate event-related desynchronization (ERD) in healthy persons. The objective of this study was to test the hypothesis that anodal tDCS could modulate ERD in patients with severe hemiparetic stroke. The participants were six patients with chronic hemiparetic stroke (mean age, 56.8 ± 9.5 years; mean time from the onset, 70.0 ± 19.6 months; Fugl-Meyer Assessment upper extremity motor score, 30.8 ± 16.5). We applied anodal tDCS (10 min, 1 mA) and sham stimulation over the affected primary motor cortex in a random order. ERD of the mu rhythm (mu ERD) with motor imagery of extension of the affected finger was assessed before and after anodal tDCS and sham stimulation. Mu ERD of the affected hemisphere increased significantly after anodal tDCS, whereas it did not change after sham stimulation. Our results show that anodal tDCS can increase mu ERD in patients with hemiparetic stroke, indicating that anodal tDCS could be used as a conditioning tool for BCI in stroke patients.
Authors:
Yuko Kasashima; Toshiyuki Fujiwara; Yayoi Matsushika; Tetsuya Tsuji; Kimitaka Hase; Junichi Ushiyama; Junichi Ushiba; Meigen Liu
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2012-07-13
Journal Detail:
Title:  Experimental brain research     Volume:  221     ISSN:  1432-1106     ISO Abbreviation:  Exp Brain Res     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-06     Completed Date:  2013-06-06     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0043312     Medline TA:  Exp Brain Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  263-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Chronic Disease
Cortical Synchronization / physiology*
Evoked Potentials, Motor / physiology*
Female
Humans
Imagination / physiology*
Male
Middle Aged
Paresis / epidemiology,  physiopathology*,  therapy
Stroke / epidemiology,  physiopathology*,  therapy
Time Factors
Transcranial Magnetic Stimulation / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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