Document Detail


Modulation of cytotoxic effect of anticancer drugs by dipyridamole in HeLa cells in vitro.
MedLine Citation:
PMID:  2285237     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exponentially growing HeLa cells were treated with various antitumor drugs and dipyridamole (DP), and the cell growth inhibition ratio was determined. Enhanced growth inhibition was found in combined treatment with DP and 5-fluorouracil, 1-hexylcarbamoyl-5-fluorouracil, methotrexate, adriamycin, daunomycin, 4'-0-tetrahydropyranyl-adriamycin, actinomycin D and vincristine. In contrast, reduction of the cytotoxic effect of cytosine arabinoside and enocitabine was found when these were combined with DP.
Authors:
H Kusumoto; Y Maehara; Y Sakaguchi; S Kohnoe; R Kumashiro; K Sugimachi
Related Documents :
20105337 - Oral cancer overexpressed 1 (oraov1) regulates cell cycle and apoptosis in cervical can...
16988227 - Actin cytoskeleton-dependent and -independent host cell invasion by trypanosoma cruzi i...
10503877 - In vivo interaction of nucleophosmin/b23 and protein c23 during cell cycle progression ...
19184457 - Gadolinium promoted proliferation and enhanced survival in human cervical carcinoma cells.
11595797 - The disease resistance signaling components eds1 and pad4 are essential regulators of t...
2527367 - Purification of scatter factor, a fibroblast-derived basic protein that modulates epith...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anticancer research     Volume:  10     ISSN:  0250-7005     ISO Abbreviation:  Anticancer Res.     Publication Date:    1990 Nov-Dec
Date Detail:
Created Date:  1991-03-15     Completed Date:  1991-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  GREECE    
Other Details:
Languages:  eng     Pagination:  1643-5     Citation Subset:  IM    
Affiliation:
Cancer Center, Kyushu University Hospital, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents / pharmacology*
Cell Division / drug effects
Cell Survival / drug effects*
Dipyridamole / pharmacology*
Drug Interactions
Hela Cells / cytology,  drug effects
Humans
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 58-32-2/Dipyridamole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of androgen, fibroblast growth factors or other various growth factors on growth of Shionogi...
Next Document:  Potentiation of BCNU-induced cytotoxicity and sister chromatid exchanges by dibromodulcitol in vitro...