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Modulation of apoptosis by ischemic preconditioning: an emerging role for miR-21.
MedLine Citation:
PMID:  23151984     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Ischemic preconditioning (IPC) is a powerful phenomenon whereby an episode of ischemic injury protects the kidney from subsequent injury. Xu et al. provide new insights into the protective effects of delayed IPC and its inhibition of apoptosis by implicating a modulatory role for the microRNA miR-21. This study adds another layer to our understanding of IPC, but also hints at the complexity of the system triggered by this process.
Authors:
Tarek M El-Achkar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Kidney international     Volume:  82     ISSN:  1523-1755     ISO Abbreviation:  Kidney Int.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0323470     Medline TA:  Kidney Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1149-51     Citation Subset:  IM    
Affiliation:
Division of Nephrology, Indiana University and the Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana, USA.
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