| Modulation of [(3)H]noradrenaline release by endothelin-1 in the rat tail artery. | |
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MedLine Citation:
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PMID: 20504724 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The effect of endothelin-1 (ET-1) on the increase in perfusion pressure and the release of noradrenaline produced by electrical field stimulation were examined in isolated perfused/superfused rat tail arteries. ET-1 (1-30 nM) increased, in an identical concentration-dependent manner, the basal perfusion pressure and the stimulation-evoked tritum overflow, whereas the basal outflow of noradrenaline was not changed by the peptide. These results show that, besides its postjunctional vasoconstrictor effect, ET-1 exerts in the rat tail artery a prejunctional action which might be involved in the modulation of stimulation-evoked noradrenaline release from postganglionic nerves. |
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Authors:
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B Bucher; D Paya; J C Stoclet |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurochemistry international Volume: 18 ISSN: 0197-0186 ISO Abbreviation: Neurochem. Int. Publication Date: 1991 |
Date Detail:
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Created Date: 2010-05-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8006959 Medline TA: Neurochem Int Country: England |
Other Details:
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Languages: eng Pagination: 455-9 Citation Subset: - |
Affiliation:
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Laboratoire de Pharmacologie Cellulaire et Moléculaire, CNRS URA 600, B.P. 24, 67401 Illkirch Cedex, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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