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Modulating the Acidity-Highly Acidic Brønsted Acids in Asymmetric Catalysis.
MedLine Citation:
PMID:  21678531     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Recently, chiral highly acidic Brønsted acids have emerged as powerful catalysts for enantioselective CC and CX bond-forming reactions. Their strong acidity renders them valuable tools for the activation of imines, carbonyl compounds, and other weakly basic substrates. As a result, new perspectives are opened and highly stereoselective transformations based on the concept of chiral contact-ion-pair catalysis can be realized. This Minireview gives an overview of the design and application of these new organocatalysts and presents recent results in this rapidly growing field.
Authors:
Magnus Rueping; Boris J Nachtsheim; Winai Ieawsuwan; Iuliana Atodiresei
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-15
Journal Detail:
Title:  Angewandte Chemie (International ed. in English)     Volume:  -     ISSN:  1521-3773     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370543     Medline TA:  Angew Chem Int Ed Engl     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Institut für Organische Chemie, RWTH Aachen, Landoltweg 1, 52074 Aachen (Germany), Fax: (+94) 241-80-92665. magnus.rueping@rwth-aachen.de.
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