Document Detail


Modular organization of frequency integration in primary auditory cortex.
MedLine Citation:
PMID:  10845073     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two fundamental aspects of frequency analysis shape the functional organization of primary auditory cortex. For one, the decomposition of complex sounds into different frequency components is reflected in the tonotopic organization of auditory cortical fields. Second, recent findings suggest that this decomposition is carried out in parallel for a wide range of frequency resolutions by neurons with frequency receptive fields of different sizes (bandwidths). A systematic representation of the range of frequency resolution and, equivalently, spectral integration shapes the functional organization of the iso-frequency domain. Distinct subregions, or "modules," along the iso-frequency domain can be demonstrated with various measures of spectral integration, including pure-tone tuning curves, noise masking, and electrical cochlear stimulation. This modularity in the representation of spectral integration is expressed by intrinsic cortical connections. This organization has implications for our understanding of psychophysical spectral integration measures such as the critical band and general cortical coding strategies.
Authors:
C E Schreiner; H L Read; M L Sutter
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Annual review of neuroscience     Volume:  23     ISSN:  0147-006X     ISO Abbreviation:  Annu. Rev. Neurosci.     Publication Date:  2000  
Date Detail:
Created Date:  2000-09-08     Completed Date:  2000-09-08     Revised Date:  2011-11-09    
Medline Journal Info:
Nlm Unique ID:  7804039     Medline TA:  Annu Rev Neurosci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  501-29     Citation Subset:  IM    
Affiliation:
Coleman Memorial Laboratory, W.M. Keck Center for Integrative Neuroscience, University of California, San Francisco 94143-0732, USA. chris@phy.ucsf.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Auditory Cortex / physiology*
Auditory Pathways / physiology
Auditory Perception / physiology*
Brain Mapping
Grant Support
ID/Acronym/Agency:
R01 DC002260-05/DC/NIDCD NIH HHS

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