Document Detail


Modified technique of isolated left lung perfusion in the rat.
MedLine Citation:
PMID:  10072615     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Isolated lung perfusion is a novel therapy for the treatment of pulmonary metastases to increase current low survival rates. Due to tumor heterogeneity, perfusion has to be evaluated in different rat species for efficacy and ideal drug regimens. The revised technique of isolated left lung perfusion as described by Wang and originally performed in the Fisher rat resulted in a high morbiditity in the Wag/Rij rat in our laboratory. Therefore, we modified techniques for intubation and anesthesia, and developed a new approach of catheterization with improved results.
Authors:
J M Hendriks; P E van Schil; E J Eyskens
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes     Volume:  31     ISSN:  0014-312X     ISO Abbreviation:  Eur Surg Res     Publication Date:  1999  
Date Detail:
Created Date:  1999-05-03     Completed Date:  1999-05-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0174752     Medline TA:  Eur Surg Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  93-6     Citation Subset:  IM    
Affiliation:
Laboratory for Experimental Surgery, University Hospital Antwerp, Belgium. j.hendriks@planetinternet.be
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MeSH Terms
Descriptor/Qualifier:
Anesthesia / methods
Animals
Catheterization / methods
Chemotherapy, Cancer, Regional Perfusion / methods*
Evaluation Studies as Topic
Intubation / methods
Lung*
Lung Neoplasms / drug therapy*,  secondary
Male
Pulmonary Artery
Rats
Species Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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