| Modified laparoscopic splenectomy: a beneficial technique for ABO-incompatible living donor renal transplantation candidates on hemodialysis. | |
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MedLine Citation:
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PMID: 18937721 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Advances in laparoscopy have enabled minimally invasive surgical treatment of splenic diseases. Even with these advances, laparoscopic splenectomy in patients on dialysis can be difficult because of tissue fragility due to the underlying renal disease. We report a safe surgical technique for laparoscopic splenectomy in patients on maintenance dialysis that is suitable for use before ABO-incompatible living donor renal transplantation (LDRTx). Between June 1972 and December 2006, a total of 800 patients underwent LDRTx in our department, including 82 patients who underwent ABO-incompatible LDRTx. Between April 2001 and December 2006 we performed laparoscopic splenectomy in 48 hemodialysis patients as a pretreatment before ABO-incompatible LDRTx. Under general anesthesia the operation was performed using a new technique, referred to as the "splenic hilum lump method." We evaluated the surgical outcomes, such as the operative time, amount of blood loss, efficacy, and complications. The mean operative time was 131.6 +/- 38.4 min and mean blood loss was 126 +/- 395 mL. Blood transfusion was required in three patients. All cases had satisfactory kidney function after LDRTx and none developed kidney graft failure due to acute rejection. Almost all patients could walk the day after laparoscopic splenectomy and were satisfied with the cosmetic appearance of the scar after wound healing. The surgical technique we report here can be safely performed on patients with renal failure who require caution because of tissue fragility. Laparoscopic splenectomy is a safe, effective and less invasive operative procedure as a pretreatment for ABO-incompatible LDRTx. |
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Authors:
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Susumu Matsuoka; Kazuharu Uchida; Yoshihiro Tominaga; Nobuaki Uno; Syuichi Simabukuro; Takahisa Hiramitsu; Norihiko Goto; Tetsuhiko Sato; Takaharu Nagasaka; Yoshihiko Watarai |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Volume: 12 ISSN: 1744-9987 ISO Abbreviation: Ther Apher Dial Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-10-21 Completed Date: 2009-01-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101181252 Medline TA: Ther Apher Dial Country: Australia |
Other Details:
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Languages: eng Pagination: 381-4 Citation Subset: IM |
Affiliation:
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Department of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan. matsuoka@nagoya2.jrc.or.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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ABO Blood-Group System
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immunology* Adult Blood Group Incompatibility / immunology, surgery* Cohort Studies Female Follow-Up Studies Graft Rejection Graft Survival Humans Japan Kidney Failure, Chronic / immunology, surgery Kidney Transplantation / methods* Laparoscopy / methods Length of Stay Living Donors* Male Middle Aged Retrospective Studies Risk Assessment Splenectomy / methods* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/ABO Blood-Group System |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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