Document Detail


Modified cold pressor test by cold application to the foot after spinal cord injury: suggestion of hemodynamic control by the spinal cord.
MedLine Citation:
PMID:  18049135     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Study hemodynamic responses to cold application to the foot (CAF) to explore the autonomic cardiovascular control by the spinal cord. DESIGN: Controlled experimental study. Hemodynamic variables were measured or calculated for 13 healthy subjects, 10 patients with traumatic T4-T6 paraplegia, and 11 patients with traumatic C4-C7 tetraplegia. Subjects were continuously monitored for heart rate (HR), blood pressure (BP), and cerebral blood-flow velocity (CBFV) from 5 mins before to 5 mins after 40-120 secs of CAF by ice water foot immersion. The recorded signals were digitized online and analyzed offline in the time and frequency domains. RESULTS: During CAF, HR increased in the control group but decreased in patients (P < 0.001). BP increased significantly in the control and tetraplegia groups (P < 0.001) and nonsignificantly in the paraplegia group. HR and BP spectral components (LF, HF, LF/HF) did not change significantly. CBFV increased significantly in the patient groups (P < 0.05) but not in the control subjects. The cerebrovascular resistance increased significantly in the control and tetraplegia groups (P < 0.001), but not in the paraplegia group. CONCLUSIONS: The findings support the presence of hemodynamic autonomic control by the spinal cord and show that responses to CAF can be used to assess its integrity.
Authors:
A Catz; V Bluvshtein; A D Korczyn; I Pinhas; I Gelernter; T Nissel; Y Vered; N M Bornstein; S Akselrod
Related Documents :
8299635 - Valsalva manoeuvre in the assessment of baroreflex sensitivity in patients with coronar...
1610775 - Noninvasive determination of baroreflex sensitivity in man by means of spectral analysis.
9557925 - Low-dose transdermal scopolamine decreases blood pressure in mild essential hypertension.
11553035 - Lack of association between qt dispersion and blood pressure response during dental sur...
1880815 - Effects of graded perfusion and isovolumic work on epicardial and venous adenosine and ...
1688835 - Crystalloid versus colloid fluid therapy after cardiac surgery.
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of physical medicine & rehabilitation / Association of Academic Physiatrists     Volume:  86     ISSN:  0894-9115     ISO Abbreviation:  Am J Phys Med Rehabil     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-30     Completed Date:  2008-01-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8803677     Medline TA:  Am J Phys Med Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  875-82     Citation Subset:  AIM; IM    
Affiliation:
Loewenstein Rehabilitation Hospital, Raanana, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Autonomic Dysreflexia / physiopathology
Cerebrovascular Circulation / physiology
Cold Temperature*
Female
Foot
Hemodynamics*
Humans
Paraplegia / rehabilitation*
Quadriplegia / rehabilitation*
Spinal Cord / physiology
Spinal Cord Injuries / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Gastrointestinal malignancies in HIV-infected or immunosuppressed patients: pathologic features and ...
Next Document:  Ultrasonographic examination on patients with chronic wrist pain: a retrospective study.