Document Detail


Modifications of local cerebral glucose utilization during circadian food-anticipatory activity.
MedLine Citation:
PMID:  16472928     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Food-anticipatory activity that animals express before a daily timed meal is considered as the behavioral output of a feeding-entrainable oscillator whose functional neuroanatomy is still unknown. In order to identify the possible brain areas involved in that timing mechanism, we investigated local cerebral metabolic rate for glucose during food-anticipatory activity produced either by a 4-h daily access to food starting 4 h after light onset or by a hypocaloric feeding provided at the same time. Local cerebral metabolic rate for glucose measured by the labeled 2-[(14)C]-deoxyglucose technique was quantified in 40 structures. In both groups of food-restricted rats, three brain regions (the nucleus of the solitary tract, the cerebellar cortex and the medial preoptic area) showed a decrease in local cerebral metabolic rate for glucose, compared with control ad libitum animals. In addition, only one structure, the paraventricular thalamic nucleus, was affected by temporal restricted feeding, and not by hypocaloric feeding, compared with ad libitum rats. By contrast, three brain regions, i.e. the intergeniculate leaflets, the paraventricular hypothalamic and the arcuate nuclei, showed specifically metabolic decreases during anticipation of hypocaloric feeding, and not during anticipation of temporal restricted feeding, compared with the ad libitum group. Expression of food-anticipatory activity appears to be regulated by an integrated neural circuit of brainstem and hypothalamic pathways, with hypocaloric feeding involving more extensive forebrain areas than temporal restricted feeding.
Authors:
A Pereira de Vasconcelos; I Bartol-Munier; C A Feillet; S Gourmelen; P Pevet; E Challet
Related Documents :
17075608 - Behavioral modes arise from a random process in the nudibranch melibe.
9158888 - Feeding and pecking behaviour in ostrich (struthio camelus) chicks in captivity.
11826888 - Food technology problems related to space feeding.
14469788 - Identical "feeding" and "rewarding" systems in the lateral hypothalamus of rats.
20605688 - Preservation technologies for fresh meat - a review.
11837998 - N-3 fatty acids and human health: defining strategies for public policy.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-02-10
Journal Detail:
Title:  Neuroscience     Volume:  139     ISSN:  0306-4522     ISO Abbreviation:  Neuroscience     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-04-04     Completed Date:  2006-07-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7605074     Medline TA:  Neuroscience     Country:  United States    
Other Details:
Languages:  eng     Pagination:  741-8     Citation Subset:  IM    
Affiliation:
Laboratory of Behavioral and Cognitive Neurosciences, CNRS UMR 7521, University Louis Pasteur, Strasbourg, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Antimetabolites / pharmacology
Behavior, Animal
Body Mass Index
Cerebral Cortex / drug effects,  metabolism*
Circadian Rhythm / physiology*
Deoxyglucose / pharmacology
Fasting / physiology
Feeding Behavior / drug effects,  physiology*
Glucose / metabolism*
Male
Motor Activity / drug effects,  physiology*
Rats
Rats, Long-Evans
Time Factors
Chemical
Reg. No./Substance:
0/Antimetabolites; 154-17-6/Deoxyglucose; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors modulate relea...
Next Document:  The roles of different subtypes of opioid receptors in mediating the nucleus submedius opioid-evoked...