Document Detail


Modification of radiation response by K and Mg aspartates in continuously irradiated rats and mice.
MedLine Citation:
PMID:  11539636     Owner:  NASA     Status:  MEDLINE    
Abstract/OtherAbstract:
Monopotassium D, L-aspartate and monomagnesium D, L-aspartate, both in the solution of 500 mg in 100 ml of drinking water administered prior to, during and after the outset of prolonged continuous irradiation increased the survival of rats and mice and improved neuromuscular coordination and physical ability of mice.
Authors:
O Chlebovsky; M Praslicka
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Advances in space research : the official journal of the Committee on Space Research (COSPAR)     Volume:  4     ISSN:  0273-1177     ISO Abbreviation:  Adv Space Res     Publication Date:  1984  
Date Detail:
Created Date:  2000-06-18     Completed Date:  2000-06-18     Revised Date:  2007-04-16    
Medline Journal Info:
Nlm Unique ID:  9878935     Medline TA:  Adv Space Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  257-62     Citation Subset:  S    
Affiliation:
Institute of General Biology, P.J. Safarik University, Kosice, Czechoslovakia.
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MeSH Terms
Descriptor/Qualifier:
Animals
Aspartic Acid / pharmacology,  therapeutic use*
Body Weight
Dose-Response Relationship, Radiation
Female
Gamma Rays*
Lymphocytes / drug effects,  radiation effects
Mice
Mice, Inbred ICR
Radiation Dosage
Radiation Injuries, Experimental / drug therapy*,  mortality
Radiation-Protective Agents / pharmacology,  therapeutic use*
Rats
Rats, Inbred Strains
Survival Rate
Time Factors
Chemical
Reg. No./Substance:
0/Radiation-Protective Agents; 56-84-8/Aspartic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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