Document Detail


Modification of microneedles using inkjet printing.
MedLine Citation:
PMID:  22125759     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In this study, biodegradable acid anhydride copolymer microneedles containing quantum dots were fabricated by means of visible light dynamic mask micro-stereolithography-micromolding and inkjet printing. Nanoindentation was performed to obtain the hardness and the Young's modulus of the biodegradable acid anhydride copolymer. Imaging of quantum dots within porcine skin was accomplished by means of multiphoton microscopy. Our results suggest that the combination of visible light dynamic mask micro-stereolithography-micromolding and inkjet printing enables fabrication of solid biodegradable microneedles with a wide range of geometries as well as a wide range of pharmacologic agent compositions.
Authors:
R D Boehm; P R Miller; S L Hayes; N A Monteiro-Riviere; R J Narayan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-10
Journal Detail:
Title:  AIP advances     Volume:  1     ISSN:  2158-3226     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101566109     Medline TA:  AIP Adv     Country:  -    
Other Details:
Languages:  ENG     Pagination:  22139     Citation Subset:  -    
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