| Modification of chitosan derivatives of environmental and biological interest: A green chemistry approach. | |
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MedLine Citation:
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PMID: 23376358 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Chitosan is a non-toxic polyaminosaccharide that is available in a variety of useful forms, and its chemical and biological properties make it a very attractive biomaterial that could be used in a wide variety of medicinal applications. This work focuses on the preparation of different chitosan derivatives by treatment with ethyl cellulose, cellulose triacetate and different carbohydrates in both neutral and slightly acidic media. It also addresses modification with glycidyltrimethyl ammonium chloride, phthalic anhydride and succinic acid derivatives. The obtained derivatives were crosslinked with glutaraldehyde. Thermo-gravimetric (TGA) and FT-IR spectroscopic analyses and electron scanning microscopy (SEM) were used to characterize the obtained products and demonstrate the success of the chitosan-modification process. The obtained products were tested for their ability to uptake transition metal ions from aqueous solutions, and their ion-uptake efficiency was determined with the aid of the ICP-AES technique. The bioactivity of some selected products was tested to study the effect of their concentrations on selected microorganisms. Burkholderia cepaci, Aspergillus niger, and Candida albicans were selected as representative examples of bacteria, yeasts and fungi, respectively. |
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Authors:
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Magdy Y Abdelaal; Tariq R Sobahi; Hossa F Al-Shareef |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-31 |
Journal Detail:
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Title: International journal of biological macromolecules Volume: - ISSN: 1879-0003 ISO Abbreviation: Int. J. Biol. Macromol. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-2-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7909578 Medline TA: Int J Biol Macromol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2013. Published by Elsevier B.V. |
Affiliation:
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Chemistry Department, Faculty of Science, King Abdulaziz University PO Box 80203, Jeddah 21589, Saudi Arabia. Electronic address: magdyabdelaal@yahoo.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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