| Modification of a High Frequency Oscillator Circuit With a Heated Expiratory Filter to Prevent Infectious Pathogen Transmission: A Bench Study. | |
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MedLine Citation:
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PMID: 22005725 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: High frequency oscillation is a safe and effective treatment for patients with acute respiratory distress syndrome, but poses a patient and caregiver risk when the circuit is disconnected. We modified the circuit to include a heated expiratory filter, eliminating the need for daily filter changes due to buildup of condensate. The purpose of the study was to determine if substitution of the filter resulted in a clinically significant change in delivered tidal volume or amplitude. We additionally compared expiratory resistance and measured efficacy for the substituted filter. METHODS: This bench study measured tidal volume and amplitude using five of each filter type across six patient setting scenarios. Filter efficacy was tested through an independent laboratory, and expiratory resistance measurements were taken after prolonged use with humidification. RESULTS: The clinically significant threshold value for tidal volume (defined as 5% difference) was excluded by the limits of agreement, confirming that use of the modified circuit does not result in alterations in tidal volume. The clinically significant threshold for amplitude (defined as 10% difference) was the same as the lower confidence interval on the lower limit of agreement, indicating it is possible for amplitude values to be different between the two filters. Filter efficacy for the substituted filter was not affected. Expiratory resistance was unchanged in the substituted filter but nearly doubled for the manufacturer's filter after 48 hours. CONCLUSIONS: Modifying the circuit to include a heated expiratory filter does not affect tidal volume, and the filter material remains efficacious during oscillation. Amplitude varies under some conditions. Preventing the need for daily filter changes reduces the risk of alveolar de-recruitment. This does not completely eliminate exposure to expired gases, but provides an additional layer of protection against occupational exposure and nosocomial spread of respiratory pathogens. Further testing in a clinical environment is necessary. |
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Authors:
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Shari I McKeown; Nicola Serreqi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-13 |
Journal Detail:
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Title: Respiratory care Volume: - ISSN: 0020-1324 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7510357 Medline TA: Respir Care Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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