| Modification of Electroosmotic Flow for a Polydimethylsiloxane Electrophoresis Microchip via Polyelectrolyte Coating. | |
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MedLine Citation:
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PMID: 22322813 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Polydimethylsiloxane has been dominantly employed as the substrate material for microchip capillary electrophoresis. The poor surface chemistry, however, generates inconsistent electroosmotic flow under the electrophoretic condition, limiting its broader applications. In this work, different polyelectrolytes, including polydiallyldimethylammonium chloride, polyvinyl sulfate, and dextran sulfate, were successfully deposited onto polydimethylsiloxane microchannel surfaces. The polyelectrolyte coated polydimethylsiloxane microchannel showed improved consistency and reproducibility in electroosmotic flow under an electric field over the uncoated native microchannel. |
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Authors:
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Zacchary D Kihm; Erik M Veen; J Devan Bergen-Hartigan; Yang Zhang; Yan Liu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry Volume: 28 ISSN: 1348-2246 ISO Abbreviation: Anal Sci Publication Date: 2012 |
Date Detail:
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Created Date: 2012-02-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8511078 Medline TA: Anal Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 183 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Northern Michigan University. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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