| Modic changes and associated features in Southern European chronic low back pain patients. | |
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MedLine Citation:
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PMID: 21558034 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND CONTEXT: Conflicting reports exist regarding the prevalence of Modic changes among low back pain (LBP) patients and factors associated with their existence. PURPOSE: To assess the prevalence of Modic changes and other findings on lumbar magnetic resonance imaging (MRI) among Spanish adult chronic LBP patients and the patient characteristics and radiological findings associated with Modic changes. STUDY DESIGN: A cross-sectional imaging study among chronic LBP patients. PATIENT SAMPLE: Four hundred eighty-seven patients (263 women and 224 men) undergoing lumbar spine MRI examination for chronic LBP. OUTCOME MEASURES: Gender, age, body mass index (BMI), lifetime smoking exposure, degree of physical activity, and image features (disc degeneration, type and extension of Modic changes, disc contour, annular tears, spinal stenosis, and spondylolisthesis). METHODS: Ten radiologists from six hospitals across six cities in Spain consecutively recruited adult patients in whom lumbar MRI had been prescribed for LBP lasting ≥3 months. Patients' characteristics and imaging findings were assessed through previously validated instruments. A multivariate logistic regression model was developed to assess the features associated with Modic changes. RESULTS: Modic changes were found in 81% of the patients. The most common was Type II (51.3%), affecting only the end plate. Variables associated with Type I changes were disc contour abnormalities, spondylolisthesis, and disc degeneration. The same variables were associated with a higher risk of Type II or any type of Modic changes, as well as being male, and having a higher BMI. CONCLUSIONS: Modic changes are found in 81% (95% confidence interval, 77-85) of adult Spanish patients in whom an MRI is prescribed for chronic LBP. Modic changes are more likely to be found in males with a high BMI, who also show disc contour abnormalities, spondylolisthesis, or disc degeneration. |
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Authors:
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Estanislao Arana; Francisco M Kovacs; Ana Royuela; Ana Estremera; Beatriz Asenjo; Helena Sarasíbar; Guillermo Amengual; Isabel Galarraga; Ana Alonso; Carlos Casillas; Alfonso Muriel; Julia Montoya; Cristina Ordóñez; Carmen Martínez; Javier Zamora; Carlos Campillo; Víctor Abraira |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The spine journal : official journal of the North American Spine Society Volume: 11 ISSN: 1878-1632 ISO Abbreviation: Spine J Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-05-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101130732 Medline TA: Spine J Country: United States |
Other Details:
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Languages: eng Pagination: 402-11 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Servicio de Radiología, Fundación Instituto Valenciano de Oncología, Valencia, Spain; Fundación Instituto de Investigación en Servicios de Salud, Valencia, Spain; Spanish Back Pain Research Network, Fundación Kovacs, Paseo de Mallorca 36, 07012 Palma de Mallorca, Spain. |
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