Document Detail

Modern tattoos cause high concentrations of hazardous pigments in skin.
MedLine Citation:
PMID:  18353031     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Modern tattoo colourants frequently consist of azo pigments that not only contain multiple impurities but also are originally produced for car paint and the dyeing of consumer goods. OBJECTIVE: In order to be able to assess the health risk of tattoos, it is important to determine the pigment concentration in human skin. METHODS: We tattooed excised pigskin and human skin with a common tattoo pigment (Pigment Red 22) under various conditions. After tattooing, we quantitatively extracted the pigment in order to determine the pigment concentration in skin. RESULTS: The concentration of pigments ranged from about 0.60 to 9.42 mg/cm(2) of tattooed skin (mean value 2.53 mg/cm(2)) depending upon the size of the pigment crystals, the pigment concentration applied to the skin surface, and the respective procedure of tattooing. CONCLUSION: In conclusion, high concentrations of colourants are injected into the skin during tattooing and based upon this quantification, a risk assessment of tattooing ought to be carried out.
Eva Engel; Francesco Santarelli; Rudolf Vasold; Tim Maisch; Heidi Ulrich; Lukas Prantl; Burkhard König; Michael Landthaler; Wolfgang Bäumler
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Contact dermatitis     Volume:  58     ISSN:  1600-0536     ISO Abbreviation:  Contact Derm.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-20     Completed Date:  2008-05-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7604950     Medline TA:  Contact Dermatitis     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  228-33     Citation Subset:  IM    
Department of Organic Chemistry, University of Regensburg, 93042 Regensburg, Germany.
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MeSH Terms
Azo Compounds / analysis*
Chromatography, High Pressure Liquid
Coloring Agents / analysis*
Microscopy, Electron, Transmission
Risk Assessment
Skin / anatomy & histology,  chemistry*
Tattooing / adverse effects*,  methods
Reg. No./Substance:
0/Azo Compounds; 0/Coloring Agents; 6448-95-9/Pigment Red 22

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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