Document Detail

Modern management of portal hypertension.
MedLine Citation:
PMID:  15667468     Owner:  NLM     Status:  MEDLINE    
The development of portal hypertension plays a major role in the pathogenesis of many of the complications of chronic liver disease. In developed countries, most patients with portal hypertension have cirrhosis, and, in this condition, portal pressure is elevated as a result of both an increase in hepatic resistance to portal perfusion and increased mesenteric blood flow. Bleeding from oesophageal varices is a major cause of mortality in patients with significant portal hypertension. This review concentrates on the recognition, prevention and acute management of this life threatening complication of cirrhosis.
J S Lubel; P W Angus
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Internal medicine journal     Volume:  35     ISSN:  1444-0903     ISO Abbreviation:  Intern Med J     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-25     Completed Date:  2005-05-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  101092952     Medline TA:  Intern Med J     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  45-9     Citation Subset:  IM    
Department of Gastroenterology, Austin Health, Melbourne, Victoria, Australia.
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MeSH Terms
Esophageal and Gastric Varices / complications
Gastrointestinal Hemorrhage / complications
Hypertension, Portal / diagnosis,  etiology,  physiopathology,  therapy*
Liver / physiopathology
Portasystemic Shunt, Transjugular Intrahepatic

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