Document Detail

Modern management and pathophysiology of ranula: literature review.
MedLine Citation:
PMID:  20054853     Owner:  NLM     Status:  In-Process    
BACKGROUND: There is a lack of consensus about the appropriate treatment of ranula. The objective of the present investigation was to produce a scientific basis for treatment.
METHODS: A review of the relevant literature is interpreted in the light of improved knowledge about the local anatomy and the pathophysiology of the salivary glands.
RESULTS: The oral and plunging ranulas are cystic extravasation mucoceles that arise from the sublingual gland and usually from a torn duct of Rivinus. The sublingual gland is a spontaneous secretor and the salivary flow is resistant to obstruction, which is caused by fibrosis induced by the extravasation. The submandibular gland is not a spontaneous secretor, is less resistant, and does not give rise to ranulas.
CONCLUSIONS: Effective treatment is removal of the involved unit of the sublingual gland or inducing sufficient fibrosis to seal the leak through which the mucus extravasates.
John D Harrison
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Head & neck     Volume:  32     ISSN:  1097-0347     ISO Abbreviation:  Head Neck     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1310-20     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley Periodicals, Inc.
Department of Oral Pathology, King's College London Dental Institute at Guy's, King's College and St Thomas' Hospitals, London, United Kingdom.
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