Document Detail

Modern concept of vascular cognitive impairment.
MedLine Citation:
PMID:  17675645     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Vascular cognitive impairment (VCI) has superseded vascular dementia and multi-infarct dementia as the concept to be used in cognitive decline due to cerebrovascular disease. METHOD: The literature was reviewed with regard to the concept of VCI and its incidence, pathophysiological substrate, clinical features and management. RESULTS: A change in the diagnostic paradigm from the current Alzheimer-based definition of vascular dementia to VCI will allow the earlier identification of cases and will identify a different population from that recognized using the current criteria for vascular dementia. CONCLUSIONS: Case identification at the earliest possible stage affords the greatest opportunity for treatment that may slow the rate of progression.
J V Bowler
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-08-04
Journal Detail:
Title:  British medical bulletin     Volume:  83     ISSN:  0007-1420     ISO Abbreviation:  Br. Med. Bull.     Publication Date:  2007  
Date Detail:
Created Date:  2007-10-18     Completed Date:  2008-05-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376542     Medline TA:  Br Med Bull     Country:  England    
Other Details:
Languages:  eng     Pagination:  291-305     Citation Subset:  IM    
Department of Clinical Neurosciences, Royal Free & University College Medical School, Hampstead Campus, Rowland Hill St., London NW3 2PF, UK.
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MeSH Terms
Aged, 80 and over
Alzheimer Disease / complications
Cerebrovascular Disorders / complications
Cognition Disorders / diagnosis,  epidemiology*,  etiology
Dementia, Vascular / diagnosis,  epidemiology*,  etiology
Diagnosis, Differential
Middle Aged
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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