Document Detail


Modern approach to managing vernal keratoconjunctivitis.
MedLine Citation:
PMID:  20425012     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vernal keratoconjunctivitis (VKC), an allergic inflammation of the conjunctiva affecting mainly children and adolescents, is categorized under the rubric of allergic conjunctivitis. Lack of uniform diagnostic and predefined staging criteria has been a bottleneck in formulating fixed guidelines to treat VKC. This lack of consensus among clinicians/researchers regarding diagnostic and grading standards has prevented us from making comparisons between the outcomes of different studies. To treat VKC, selection of a drug from many available options should be based on the duration and frequency of symptoms, grade and inflammation of giant papillae, and severity of corneal involvement. Consideration also should be given to the patient's specific needs. The basic tenet of treatment is optimal control of symptoms with a minimum of toxic side effects resulting from prolonged use of medication.
Authors:
Sunil Kumar; Nitin Gupta; Anthony J Vivian
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current allergy and asthma reports     Volume:  10     ISSN:  1534-6315     ISO Abbreviation:  Curr Allergy Asthma Rep     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-05     Completed Date:  2010-08-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101096440     Medline TA:  Curr Allergy Asthma Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  155-62     Citation Subset:  IM    
Affiliation:
Toronto Western Hospital, 5th Floor West Wing, 339 Bathurst Street, Toronto, Ontario, M5T 2S8, Canada. sunkaru79@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex Hormones / therapeutic use
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Antimetabolites / therapeutic use
Conjunctiva / immunology*
Conjunctivitis, Allergic* / diagnosis,  drug therapy,  immunology
Cornea / immunology*
Histamine Antagonists / therapeutic use
Humans
Immunologic Factors / therapeutic use
Patient Education as Topic
Severity of Illness Index
Vasoconstrictor Agents / therapeutic use
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/Antimetabolites; 0/Histamine Antagonists; 0/Immunologic Factors; 0/Vasoconstrictor Agents

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