Document Detail

Moderate intravenous sedation for office-based full face laser resurfacing using a continuous infusion propofol pump.
MedLine Citation:
PMID:  16003614     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The purpose of this study was to compare the anesthetic requirements and hemodynamic and oxygenation variables involved between the bolus midazolam/fentanyl intravenous sedation-analgesia technique, and the same technique combined with continuous-infusion propofol. PATIENTS AND METHODS: This was a retrospective chart analysis of 41 consecutive patients undergoing full-face carbon dioxide laser resurfacing with either bolus midazolam/fentanyl (n = 15) or midazolam/fentanyl with continuous propofol infusion anesthesia (n = 26) techniques. Data recorded were noninvasive baseline and intraoperative hemodynamic measurements at 5-minute intervals for systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), pulse pressure (PP), pulse (P), and rate-pressure product (RPP), respiratory rate (RR), and oxygen saturation (SpO2). Data collected were reported as mean values with standard deviation. Statistical analyses were performed with the Student's t test and found statistically significant for P < .05. RESULTS: Statistically significant decreases in averages were seen in SBP (P < .001), DBP (P = .02), MAP (P = .004), P (P < .00l), RPP (P < .00l), and RR (P < .001), but not PP (P = .4) and SpO2 (P = .08) in the midazolam/fentanyl/continuous propofol infusion group compared with the midazolam/fentanyl only group. Changes from baseline were statistically significant only for MAP (P = .04), but statistically insignificant for all other measurements, SBP (P = .7), DBP (P = .4), P (P = .95), PP (P = .97), RPP (P = .6), RR (P = .6), and SpO2 (P = .4). Statistically significant smaller amounts of midazolam (P = .01) and fentanyl (P < .001) were used in the midazolam/fentanyl/continuous propofol infusion pump group. Length of procedure was statistically insignificant between groups (P = .4). Conclusion The addition of a continuous propofol pump maintained hemodynamic and oxygenation values close to baseline, while decreasing the amount of respiratory depressing opiates administered and without affecting the length of the procedure.
Joseph E Cillo; Richard Finn
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons     Volume:  63     ISSN:  0278-2391     ISO Abbreviation:  J. Oral Maxillofac. Surg.     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-07-08     Completed Date:  2005-07-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8206428     Medline TA:  J Oral Maxillofac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  903-7     Citation Subset:  AIM; D; IM    
Oral and Maxillofacial Surgery, parkland Memorial Hospital, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
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MeSH Terms
Aged, 80 and over
Ambulatory Surgical Procedures
Anesthesia, Dental / methods*
Anesthesia, Intravenous / instrumentation
Anesthetics, Intravenous / administration & dosage*
Anesthetics, Local / administration & dosage
Blood Pressure / drug effects
Carbon Dioxide
Conscious Sedation / methods*
Facial Dermatoses / etiology,  surgery*
Heart Rate / drug effects
Infusion Pumps
Keratosis / etiology,  surgery*
Laser Therapy / methods*
Middle Aged
Oxygen / blood
Propofol / administration & dosage*
Retrospective Studies
Sunlight / adverse effects
Reg. No./Substance:
0/Anesthetics, Intravenous; 0/Anesthetics, Local; 124-38-9/Carbon Dioxide; 2078-54-8/Propofol; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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