| Moderate inflammatory reaction during experimental Escherichia coli mastitis in primiparous cows. | |
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MedLine Citation:
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PMID: 15259223 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nineteen primiparous cows were experimentally infected in 2 quarters with 1 x 10(4) (group A) or 1 x 10(6) (group B) cfu of Escherichia coli P4:O32 per quarter within 2 to 4 wk after parturition. Blood and milk samples were collected from all primiparous cows at regular time intervals from d -4 to d +3 relative to inoculation. Milk production rapidly decreased in both groups during E. coli mastitis, but recovery appeared to be faster in group B at d + 1 postinfusion (p.i.). The milk production losses in the noninfected quarters were substantial on the day of inoculation, which is probably due to pronounced systemic effects. However, on d + 2 p.i. milk production in the noninfected quarters nearly reached preinfection levels, indicating a moderate clinical severity following intramammary inoculation. None of the other severity criteria evolved towards a severe response pattern. Reticulorumen motility was inhibited in both groups during E. coli mastitis. The clinical episode was short lasting in both groups. Rectal temperature, heart rate, blood leukocyte count, number of colony-forming units, milk somatic cell count and several indicators for the disintegration of the blood-milk barrier returned to normal values within 24 to 72 h p.i. Primiparous cows reacted with a moderate inflammatory response following intramammary infusion with a relatively high dose of E. coli. Despite the use of a high inoculum dose, primiparous cows in both groups showed pronounced resistance against severe intramammary E. coli infection. A possible effect of the inoculum dose could be present, however, further research into the effect of the inoculum dose on the inflammatory response should be performed. |
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Authors:
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F Vangroenweghe; L Duchateau; C Burvenich |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of dairy science Volume: 87 ISSN: 0022-0302 ISO Abbreviation: J. Dairy Sci. Publication Date: 2004 Apr |
Date Detail:
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Created Date: 2004-07-19 Completed Date: 2004-08-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985126R Medline TA: J Dairy Sci Country: United States |
Other Details:
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Languages: eng Pagination: 886-95 Citation Subset: IM |
Affiliation:
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Ghent University, Faculty of Veterinary Medicine, Department of Physiology, Biochemistry, and Biometrics, 9820 Merelbeke, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Temperature Cattle Cell Count Colony Count, Microbial Escherichia coli Infections / pathology, veterinary* Female Inflammation / pathology, veterinary* Leukocyte Count Mastitis, Bovine / microbiology*, pathology* Milk / cytology Neutrophils Parity* Rectum |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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