Document Detail

Moderate exercise does not enhance the positive effect of estrogen on bone mineral density in postmenopausal women.
MedLine Citation:
PMID:  1834319     Owner:  NLM     Status:  MEDLINE    
We studied the effects of physical activity and two types of estrogen treatment in a prospective study in 78 healthy postmenopausal women. A control group and two treatment groups receiving estradiol valerate and medroxyprogesterone acetate in 1- or 3-month cycles were monitored for 1 year. Half of each group took part in an exercise program. Lumbar and femoral bone mineral density increased in both of the estrogen-treatment groups. Physical exercise with estrogen treatment did not result in further increases in bone mineral densities.
J Heikkinen; E Kurttila-Matero; E Kyllönen; J Vuori; T Takala; H K Väänänen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Calcified tissue international     Volume:  49 Suppl     ISSN:  0171-967X     ISO Abbreviation:  Calcif. Tissue Int.     Publication Date:  1991  
Date Detail:
Created Date:  1991-11-26     Completed Date:  1991-11-26     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7905481     Medline TA:  Calcif Tissue Int     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S83-4     Citation Subset:  IM; S    
Deaconess Institute of Oulu, Finland.
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MeSH Terms
Bone Density / drug effects*,  physiology
Estradiol / analogs & derivatives,  therapeutic use
Estradiol Congeners / therapeutic use*
Exercise / physiology*
Medroxyprogesterone / analogs & derivatives,  therapeutic use
Medroxyprogesterone Acetate
Middle Aged
Osteoporosis, Postmenopausal / prevention & control
Prospective Studies
Reg. No./Substance:
0/Estradiol Congeners; 50-28-2/Estradiol; 520-85-4/Medroxyprogesterone; 71-58-9/Medroxyprogesterone Acetate; 979-32-8/estradiol valerate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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