Document Detail


Moderate drinking and reduced risk of heart disease.
MedLine Citation:
PMID:  10890794     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although heavier drinkers are at increased risk for some heart diseases, moderate drinkers are at lower risk for the most common form of heart disease, coronary artery disease (CAD) than are either heavier drinkers or abstainers. This association has been demonstrated in large-scale epidemiological studies from many countries. Abstainers may share traits potentially related to CAD risk, such as psychological characteristics, dietary habits, and physical exercise patterns. However, evidence supports a direct protective effect of alcohol, even after data have been adjusted for the presence of these factors. The alcohol-CAD relationship is also independent of the hypothetically increased risk status among abstainers who stopped drinking for medical reasons. All alcoholic beverages protect against CAD, although some additional protection may be attributable to personal traits or drinking patterns among people who share some beverage preferences or to nonalcohol ingredients in specific beverages. Alcohol's protective effect may result from favorable alterations in blood chemistry and the prevention of clot formation in arteries that deliver blood to the heart muscle. Because CAD accounts for a large proportion of total mortality, the risk of death from all causes is slightly lower among moderate drinkers than among abstainers, but heavier drinkers are at considerably higher total mortality risk.
Authors:
A L Klatsky
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism     Volume:  23     ISSN:  1535-7414     ISO Abbreviation:  Alcohol Res Health     Publication Date:  1999  
Date Detail:
Created Date:  2000-08-15     Completed Date:  2000-08-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100900708     Medline TA:  Alcohol Res Health     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  15-23     Citation Subset:  IM    
Affiliation:
Department of Medicine, Kaiser Permanente Medical Center, Oakland, California, USA.
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MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking*
Heart Diseases / prevention & control*
Humans

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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