Document Detail

Moderate alcohol use during pregnancy and decreased infant birth weight.
MedLine Citation:
PMID:  596498     Owner:  NLM     Status:  MEDLINE    
Maternal alcoholism during pregnancy may result in severe prenatal growth deficiency. In this prospective study, the relationship of moderate maternal alcohol consumption to infant birth weight is explored. Subjects were 263 paying members of a health maintenance organization who delivered single live children. Their alcohol consumption before pregnancy, and in early and late pregnancy, was estimated. In order to control for smoking, which is strongly related to both infant birth weight and maternal alcohol use, the sample was selected so that similar proportions of smokers were represented in both light and heavier drinkers. Multiple linear regression was employed. A regression equation was computed for each of the three periods in which drinking was estimated. Independent variables entered into the equation were maternal age, height, parity, daily cigarettes, alcohol use in the period, and gestational age and sex of child. The regression of birth weight on these variables revealed a significant relationship (p less than or equal to .01) with alcohol consumption in two of the periods. Ingestion of an average of one ounce of absolute alcohol daily before pregnancy was associated with an average decrease in birth weight of 91 grams; the same amount ingested in late pregnancy was associated with a decrease of 160 grams. The associations were independent of the other variables entered into the equation, and in particular, of tobacco use.
R E Little
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American journal of public health     Volume:  67     ISSN:  0090-0036     ISO Abbreviation:  Am J Public Health     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-02-23     Completed Date:  1978-02-23     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  1254074     Medline TA:  Am J Public Health     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1154-6     Citation Subset:  AIM; IM    
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MeSH Terms
Alcohol Drinking*
Birth Weight / drug effects*
Infant, Newborn
Maternal Age
Pregnancy Complications*
Smoking / complications
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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