| Models of place and grid cell firing and theta rhythmicity. | |
| | |
MedLine Citation:
|
PMID: 21820895 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Neuronal firing in the hippocampal formation (HF) of freely moving rodents shows striking examples of spatialorganization in the form of place, directional, boundary vector and grid cells. The firing of place and grid cells shows an intriguing form of temporal organization known as 'theta phase precession'. We review the mechanisms underlying theta phase precession of place cell firing, ranging from membrane potential oscillations to recurrent connectivity, and the relevant intra-cellular and extra-cellular data. We then consider the use of these models to explain the spatial structure of grid cell firing, and review the relevant intra-cellular and extra-cellular data. Finally, we consider the likely interaction between place cells, grid cells and boundary vector cells in estimating self-location as a compromise between path-integration and environmental information. |
| | |
Authors:
|
Neil Burgess; John O'Keefe |
Related Documents
:
|
21515585 - C. albicans increases cell wall mannoprotein, but not mannan, in response to blood, ser... 21814285 - Mechanism of cell death resulting from dna interstrand cross-linking in mammalian cells. 22434575 - Biciliated ependymal cell proliferation contributes to spinal cord growth. 22246215 - Assessment of the novel tubulin-binding agent eht 6706 in combination with ionizing rad... 22844365 - Reduced migration of ishikawa cells associated with downregulation of aquaporin-5. 19539755 - Krüppel-like factor 4, a "pluripotency transcription factor" highly expressed in male ... |
Publication Detail:
|
Type: Journal Article; Review Date: 2011-08-04 |
Journal Detail:
|
Title: Current opinion in neurobiology Volume: 21 ISSN: 1873-6882 ISO Abbreviation: Curr. Opin. Neurobiol. Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-11-23 Completed Date: 2012-03-20 Revised Date: 2013-04-29 |
Medline Journal Info:
|
Nlm Unique ID: 9111376 Medline TA: Curr Opin Neurobiol Country: England |
Other Details:
|
Languages: eng Pagination: 734-44 Citation Subset: IM |
Copyright Information:
|
Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
|
UCL Institute of Cognitive Neuroscience, 17 Queen Square, London WC1N 3AR, UK; UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Action Potentials
/
physiology* Animals Hippocampus / cytology*, physiology Humans Models, Neurological* Neurons / classification, physiology* Theta Rhythm / physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
082507//Wellcome Trust; G0501672//Medical Research Council; G0501672(76328)//Medical Research Council |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Predictive factors for flatfoot: The role of age and footwear in children in urban and rural communi...
Next Document: Experimental study of the anaerobic urban wastewater treatment in a submerged hollow-fibre membrane ...