Document Detail


Modelling exercise-induced pulmonary hemorrhage in racing thoroughbreds.
MedLine Citation:
PMID:  1476955     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exercise-induced pulmonary hemorrhage (EIPH) affects a large portion of racing thoroughbred horses. Sites of hemorrhage and causal mechanisms remain unestablished. Our mathematical model was constructed to test the hypothesis that EIPH could be caused by a combination of respiratory and circulatory mechanical factors occurring during exercise. Various physiological data for respiration, blood circulation and exercise were incorporated into the model. Results show that inhalation pressure drops across airway resistances become great enough during exercise to cause rupture of capillaries for both bronchial and pulmonary systems.
Authors:
A T Johnson; L R Soma; C Ferouz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering     Volume:  4     ISSN:  0921-3775     ISO Abbreviation:  Front Med Biol Eng     Publication Date:  1992  
Date Detail:
Created Date:  1993-02-11     Completed Date:  1993-02-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9011464     Medline TA:  Front Med Biol Eng     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  271-89     Citation Subset:  IM; S    
Affiliation:
Agricultural Engineering Department, University of Maryland, College Park 20742.
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MeSH Terms
Descriptor/Qualifier:
Airway Resistance / physiology
Animals
Biomechanics
Blood Pressure / physiology*
Capillaries / physiology
Exercise*
Hemorrhage / physiopathology,  veterinary*
Horse Diseases / etiology*,  physiopathology
Horses
Humans
Lung Diseases / physiopathology,  veterinary*
Models, Biological*
Pressure
Pulmonary Circulation / physiology
Species Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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