Document Detail

Modelling evolving populations.
MedLine Citation:
PMID:  9093555     Owner:  NLM     Status:  MEDLINE    
A formalism is presented for modelling the evolutionary dynamics of a population of gene sequences. The formalism was originally developed for describing genetic algorithms. In this paper the formalism is elaborated by considering the evolution of an ensemble of populations. This allows the evolution to be modelled more accurately. To illustrate the formalism the problem of a population of gene sequences evolving in a multiplicative fitness landspace is considered. A comparison with simulations is made and shows very good agreement. More complicated problems have already been investigated including sexual recombination and evolution in a multi-valleyed fitness landscape. These results will be briefly reviewed.
A Prügel-Bennett
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of theoretical biology     Volume:  185     ISSN:  0022-5193     ISO Abbreviation:  J. Theor. Biol.     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-04-30     Completed Date:  1997-04-30     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0376342     Medline TA:  J Theor Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  81-95     Citation Subset:  IM    
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MeSH Terms
Base Sequence
Computer Simulation*
Genetics, Population*
Models, Genetic*

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