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Modelling the costs of care of hypertension in patients with metabolic syndrome and its consequences, in Germany, Spain and Italy.
MedLine Citation:
PMID:  20405160     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The presence of metabolic syndrome in patients with hypertension significantly increases the risk of cardiovascular disease, type 2 diabetes and mortality. Our aim is to estimate the economic burden to the health service of metabolic syndrome (MetS) in patients with hypertension and its consequences, in three European countries in 2008, and to forecast future economic burden in 2020 using projected demographic estimates and assumptions around the growth of MetS. An age-, sex- and risk group-structured prevalence-based cost of illness model was developed using the United States Adult Treatment Panel III of the National Cholesterol Education Program criteria to define MetS. Data sources included published information and public use databases on disease prevalence, incidence of cardiovascular events, prevalence of type 2 diabetes, treatment patterns and cost of management in Germany, Spain and Italy. The economic burden to the health service of MetS in patients with hypertension has been estimated at 24,427 <euro>, 1,900 <euro> and 4,877 <euro> million in Germany, Spain and Italy, and is forecast to rise by 59, 179 and 157%, respectively, by 2020. The largest components of costs included the management of prevalent type 2 diabetes and incident cardiovascular events. Mean annual costs per hypertensive patient were around three-fold higher in subjects with MetS compared to those without and rose incrementally with the additional number of MetS components present. In conclusion, the presence of MetS in patients with hypertension significantly inflates economic burden, and costs are likely to increase in the future due to an aging population and an increase in the prevalence of components of MetS.
Authors:
Eberhard Wille; Jürgen Scholze; Eduardo Alegria; Claudio Ferri; Sue Langham; Warren Stevens; David Jeffries; Kerstin Uhl-Hochgraeber
Publication Detail:
Type:  Journal Article     Date:  2010-04-20
Journal Detail:
Title:  The European journal of health economics : HEPAC : health economics in prevention and care     Volume:  12     ISSN:  1618-7601     ISO Abbreviation:  Eur J Health Econ     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-04-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101134867     Medline TA:  Eur J Health Econ     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  205-18     Citation Subset:  IM    
Affiliation:
Fakultät für Volkswirtschaftslehre, L 7, 3-5, 2. OG, Raum 21, 68131, Mannheim, Germany, wille@uni-mannheim.de.
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