Document Detail


Modeling and simulation of competition between two microorganisms for a single inhibitory substrate in a biofilm reactor.
MedLine Citation:
PMID:  10578096     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A simple biofilm model was developed to simulate the competition between two microorganisms for a common inhibitory substrate. The following assumptions were made for the simulations: (1) the biofilm has a uniform thickness and is composed of 5 segments, (2) growth of two microorganisms A and B which utilize the common substrate is expressed by the Haldane kinetics with a spatial limitation term and is independent of the other microorganism in the biofilm reactor, and (3) diffusion of the substrate, movement of the microorganisms, and continuous loss of the biomass by shearing are expressed by Fick's Law-type equations. The qualitative behavior of the biofilm reactor is characterized by five regions, I-V, depending on the operation conditions, the substrate concentration in feed, and the dilution rate. In region I, both microorganisms are washed out of the biofilm reactor. In region II, microorganism B is washed out, and in region III, microorganism A is washed out of the biofilm. In region IV, both microorganisms coexist with one another. In region V, both microorganisms coexist with a sustained oscillatory behavior. Convergence to regions I-V depends on the initial conditions. In regions II-V, washout of either or both microorganisms is also observed with initial conditions too far away.
Authors:
S Soda; E Heinzle; M Fujita
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biotechnology and bioengineering     Volume:  66     ISSN:  0006-3592     ISO Abbreviation:  Biotechnol. Bioeng.     Publication Date:  1999  
Date Detail:
Created Date:  2000-02-07     Completed Date:  2000-02-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7502021     Medline TA:  Biotechnol Bioeng     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  258-64     Citation Subset:  IM; S    
Copyright Information:
Copyright 1999 John Wiley & Sons, Inc.
Affiliation:
Department of Environmental Engineering, Osaka University, Yamada-oka 2-1, Suita, Osaka, 565-0871 Japan.
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MeSH Terms
Descriptor/Qualifier:
Biofilms / growth & development
Bioreactors*
Biotechnology
Diffusion
Microbiology
Models, Biological*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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