Document Detail

Modeling the pediatric paradox: birth weight by gestational age.
MedLine Citation:
PMID:  19350763     Owner:  NLM     Status:  MEDLINE    
The "pediatric paradox" of African versus European American infant mortality is often observed with respect to birth weight, but rarely to gestational age, even though the two measures are biologically related. This paper models the pediatric paradox by birth weight and gestational age simultaneously, using Covariate Density Defined mixture of logistic regressions (CDDmlr) fitted to 1985-1988 New York State births. The model controls for unobserved heterogeneity and isolates the pediatric paradox in the "compromised" subpopulation. The paradox is not limited to low birth weights and/or short gestational ages, but surrounds the normal birth range. Nevertheless, the pediatric paradox is only observed in the marginal distribution of birth weight and not the marginal distribution of gestational age. These results are consistent with the hypothesis that higher fetal losses in the "compromised" subpopulation may be responsible for the pediatric paradox and that African versus European American infant mortality differentials are underestimated.
Timothy B Gage; Fu Fang; Howard Stratton
Related Documents :
16647403 - Longitudinal changes in bone health as assessed by the speed of sound in very low birth...
15030013 - Pathways of the determinants of unfavourable birth outcomes in kenya.
16051623 - Baroreceptor reflex sensitivity in human neonates: the effect of postmenstrual age.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Biodemography and social biology     Volume:  54     ISSN:  1948-5565     ISO Abbreviation:  Biodemography Soc Biol     Publication Date:  2008  
Date Detail:
Created Date:  2009-04-08     Completed Date:  2009-06-30     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  101500303     Medline TA:  Biodemography Soc Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  95-112     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
African Continental Ancestry Group
Birth Weight*
Confidence Intervals
European Continental Ancestry Group
Gestational Age*
Infant Mortality / trends*
Infant, Newborn
Logistic Models
Models, Biological*
Multivariate Analysis
United States
Grant Support
HD37405/HD/NICHD NIH HHS; R01 HD037405/HD/NICHD NIH HHS; R01 HD037405-01A1/HD/NICHD NIH HHS; R01 HD037405-02/HD/NICHD NIH HHS; R01 HD037405-03/HD/NICHD NIH HHS; R01 HD037405-04A1/HD/NICHD NIH HHS; R01 HD037405-05/HD/NICHD NIH HHS; R01 HD037405-06/HD/NICHD NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A cohort study of tuberculosis and influenza mortality in the twentieth century.
Next Document:  Blood, sweat, and tears: embedding biological samples in social science research on children.