Document Detail


Modeling methodology for vascular input impedance determination and interpretation.
MedLine Citation:
PMID:  8175545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The significance of pulse wave reflections in the pulmonary vascular system is elaborated using a new method to determine the broadband frequency response of input impedance up to frequencies of 100 Hz. A simple data model, based on the signal construct of a wavelet, is used to generalize and reconcile the common approaches to vascular frequency response estimation so that an accurate response can be calculated from physiological waveforms. Input impedance interpretation is accomplished using a structural and functional modeling methodology. To identify internal structural system properties, the methodology of inverse scattering is used to relate observed pulse wave echoes in the frequency response to a longitudinal distribution of reflection sites of anatomic significance. To identify functional interactions with pulmonary vascular wave mechanics, a time series analysis methodology is proposed to describe vascular interactions using a generalized principle of superposition. The methods of determination and interpretation are applied to a sample pressure-flow data set from the pulmonary circulation of a lamb experiencing vascular-ventilatory interaction. The example suggests that the frequency response is consistent with a discrete longitudinal distribution of reflection sites that may be affected by the ventilator.
Authors:
S H Bennett
Related Documents :
15587975 - An evaluation of a bayesian method of dose escalation based on bivariate binary responses.
18568865 - Stress biology and hormesis: the yerkes-dodson law in psychology--a special case of the...
20682245 - Hill coefficients of a polymodal monod-wyman-changeux model for ion channel gating.
16223655 - The structural equation modeling technique did not show a response shift, contrary to t...
22874265 - Standardizing intensive care device data to enable secondary usages.
22895165 - Selection of key ambient particulate variables for epidemiological studies - applying c...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  76     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1994 Jan 
Date Detail:
Created Date:  1994-06-06     Completed Date:  1994-06-06     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  455-84     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of California, Davis 95616.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Newborn
Blood Pressure / physiology
Models, Biological
Pulmonary Circulation / physiology*
Sheep
Vascular Resistance / physiology*
Viscosity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Distribution of surfactant and ventilation in surfactant-treated preterm lambs.
Next Document:  Measurement of plasma volume in rats with use of fluorescent-labeled albumin molecules.