| Modeling developmental patterns of spontaneous activity. | |
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MedLine Citation:
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PMID: 21684148 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Spontaneous activity is found in many regions of the developing nervous system; such activity is thought to be instructive for guiding developmental processes. In particular, the developing retina generates correlated patterns of activity known as retinal waves. We review the main theoretical models that have been developed to study the mechanisms for generation and propagation of retinal waves. Much of the progress in this field has been due to the close interaction between experimentalists and theorists in analyzing and modeling spontaneous activity. We conclude by describing spontaneous activity models in other systems and suggestions for future modeling work. |
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Authors:
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Julijana Gjorgjieva; Stephen J Eglen |
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Publication Detail:
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Type: Journal Article; Review Date: 2011-06-16 |
Journal Detail:
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Title: Current opinion in neurobiology Volume: 21 ISSN: 1873-6882 ISO Abbreviation: Curr. Opin. Neurobiol. Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-11-23 Completed Date: 2012-03-20 Revised Date: 2013-02-26 |
Medline Journal Info:
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Nlm Unique ID: 9111376 Medline TA: Curr Opin Neurobiol Country: England |
Other Details:
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Languages: eng Pagination: 679-84 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
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Cambridge Computational Biology Institute, Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge CB3 0WA, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Humans Models, Neurological* Neurons / classification, physiology* Retina / cytology*, growth & development* Vision, Ocular / physiology* Visual Pathways / physiology |
| Grant Support | |
ID/Acronym/Agency:
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083205//Wellcome Trust |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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