| Model-based nonlinear inverse reconstruction for T2 mapping using highly undersampled spin-echo MRI. | |
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MedLine Citation:
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PMID: 21780234 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: To develop a model-based reconstruction technique for T2 mapping based on multi-echo spin-echo MRI sequences with highly undersampled Cartesian data encoding. MATERIALS AND METHODS: The proposed technique relies on a nonlinear inverse reconstruction algorithm which directly estimates a T2 and spin-density map from a train of undersampled spin echoes. The method is applicable to acquisitions with single receiver coils but benefits from multi-element coil arrays. The algorithm is validated for trains of 16 spin echoes with a spacing of 10 to 12 ms using numerical simulations as well as human brain MRI at 3 Tesla (T). RESULTS: When compared with a standard T2 fitting procedure using fully sampled T2-weighted images, and depending on the available signal-to-noise ratio and number of coil elements, model-based nonlinear inverse reconstructions for both simulated and in vivo MRI data yield accurate T2 estimates for undersampling factors of 5 to 10. CONCLUSION: This work describes a promising strategy for T2-weighted MRI that simultaneously offers accurate T2 relaxation times and properly T2-weighted images at arbitrary echo times. For a standard spin-echo MRI sequence with Cartesian encoding, the method allows for a much higher degree of undersampling than obtainable by conventional parallel imaging. J. Magn. Reson. Imaging 2011;. © 2011 Wiley-Liss, Inc. |
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Authors:
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Tilman J Sumpf; Martin Uecker; Susann Boretius; Jens Frahm |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 34 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-07-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 420-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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Biomedizinische NMR Forschungs GmbH am Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany. tsumpf@gwdg.de. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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