Document Detail

Model Reference Adaptive Scheme for Multi-drug Infusion for Blood Pressure Control.
MedLine Citation:
PMID:  21926436     Owner:  NLM     Status:  In-Data-Review    
Using multiple interacting drugs to control both the mean arterial pressure (MAP) and cardiac output (CO) of patients with different sensitivity to drugs is a challenging task which this paper attempts to address. A multivariable model reference adaptive control (MRAC) algorithm is developed using a two-input, two-output patient model. The control objective is to maintain the homodynamic variables MAP and CO at the normal values by simultaneously administering two drugs; sodium nitroprusside (SNP) and dopamine (DPM). Computer simulations were carried out to investigate the performance of this controller. The results show that the proposed adaptive scheme is robust with respect to disturbances and variations in model parameters.
Saleh Enbiya; Fatima Mahieddine; Alamgir Hossain
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Publication Detail:
Type:  Journal Article     Date:  2011-09-15
Journal Detail:
Title:  Journal of integrative bioinformatics     Volume:  8     ISSN:  1613-4516     ISO Abbreviation:  J Integr Bioinform     Publication Date:  2011  
Date Detail:
Created Date:  2011-09-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101503361     Medline TA:  J Integr Bioinform     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  173     Citation Subset:  IM    
School of Computing, Informatics and Media, University of Bradford, UK.
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