| Mode of delivery and neonatal survival of infants with gastroschisis in Australia and New Zealand. | |
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MedLine Citation:
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PMID: 18779007 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of the study was to examine the short-term outcome of infants with gastroschisis by route of delivery, comparing vaginal delivery vs elective and emergency cesarean delivery (CD). METHODS: Six hundred thirty-one infants with gastroschisis (International Classification of Diseases, 10th Revision: Q79.3) were admitted to the Australian and New Zealand Neonatal Network during 1997 to 2005. Multivariate Cox proportional hazards regression analysis was performed to adjust for case-mix and significant baseline characteristics. RESULTS: During the study period, 631 infants with gastroschisis were admitted to the collaborating centers. Of these, 343 (54.4%) infants were delivered vaginally, whereas 288 (45.6%) were delivered by cesarean birth. Of the latter, 148 (23.4%) were elective and 140 (22.2%) were emergency. There was an increasing trend of CD from 41.1% in 1997 to 69.0% in 2005. Forty-seven (7.4%) infants died; 30 (8.7%) in the vaginal, 9 (6.4%) in the emergency, and 8 (5.4%) in the elective CD group. There was no difference in rate of proven infection, duration of ventilation, or length of neonatal intensive care unit stay between the 3 groups. After controlling for prematurity, low birth weight, and outborn birth, the risk for neonatal demise was similar in both the vaginal and CD infants (adjusted hazard ratio, 1.486; 95% confidence interval, 0.814-2.713; P = .197). Stratifying the CD (emergency vs elective) gave similar results. CONCLUSION: Infants with gastroschisis appear to be safely delivered vaginally. |
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Authors:
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Mohamed E Abdel-Latif; Srinivas Bolisetty; Samanthi Abeywardana; Kei Lui; |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of pediatric surgery Volume: 43 ISSN: 1531-5037 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-09-09 Completed Date: 2009-02-11 Revised Date: 2009-04-16 |
Medline Journal Info:
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Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1685-90 Citation Subset: IM |
Affiliation:
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Department of Newborn Care, Royal Hospital for Women, Randwick, NSW 2031, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Australia Cesarean Section Delivery, Obstetric* Emergency Treatment Female Gastroschisis / mortality* Humans Infant, Newborn Male New Zealand Retrospective Studies Survival Rate |
| Comments/Corrections | |
Comment In:
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J Pediatr Surg. 2009 Mar;44(3):657-8; author reply 658-9
[PMID:
19302878
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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