Document Detail

Mobilization of visceral and subcutaneous adipose tissue in response to energy restriction and exercise.
MedLine Citation:
PMID:  7942575     Owner:  NLM     Status:  MEDLINE    
The effects of energy restriction (diet) in combination with either aerobic (DA) or resistance exercise (DR) on adipose tissue (AT) distribution were evaluated in 24 obese women (DA, n = 10; DR, n = 14). AT distribution was measured by magnetic resonance imaging (MRI). Comparison between groups demonstrated that the relative losses observed for body weight, subcutaneous AT (SAT), and visceral AT (VAT) volume were not significantly different (P > 0.05). A significant reduction in the volume ratio of VAT to SAT was observed for both groups (P < 0.01). Comparison of arm, abdomen and torso, and lower-body regions revealed that the regional mobilization of SAT was not significantly different between groups (P > 0.05) and that for both groups there was a preferential mobilization of SAT from the abdominal region (P < 0.05). Within the VAT depot, significant reductions were observed for both intraperitoneal and extraperitoneal AT (P < 0.01). These findings suggest that the combination of moderate energy restriction and either resistance or aerobic exercise induces significant reductions in VAT and SAT, with a preferential loss of VAT, and are thus effective means of reducing total and upper-body obesity in obese women.
R Ross; J Rissanen
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  60     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1994-11-08     Completed Date:  1994-11-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  695-703     Citation Subset:  AIM; IM    
School of Physical and Health Education, Queen's University, Ontario, Canada.
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MeSH Terms
Adipose Tissue / pathology*
Body Constitution
Diet, Reducing*
Energy Intake
Magnetic Resonance Imaging
Middle Aged
Obesity / diet therapy,  pathology*,  therapy*

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