Document Detail

Mixed connective tissue disease with pulmonary hypertension: a clinical and pathological study.
MedLine Citation:
PMID:  3668989     Owner:  NLM     Status:  MEDLINE    
Clinical and autopsy findings of 2 cases with mixed connective tissue disease (MCTD) associated with severe pulmonary hypertension are reported. Both cases showed marked intimal and medial thickening in small and medium sized pulmonary arteries. In one of the cases plexiform lesions, endarteritis obliterans, and fibrous intimal thickening of the pulmonary veins were recognized. In some cases with MCTD, pulmonary hypertension develops due to pulmonary vascular lesions which are similar to those of primary pulmonary hypertension.
Y Hosoda; Y Suzuki; M Takano; T Tojo; M Homma
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  14     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1987 Aug 
Date Detail:
Created Date:  1987-11-23     Completed Date:  1987-11-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  826-30     Citation Subset:  IM    
Department of Pathology and Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
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MeSH Terms
Hypertension, Pulmonary / etiology*,  pathology
Middle Aged
Mixed Connective Tissue Disease / complications*,  pathology
Pulmonary Artery / pathology

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